| Cyclin-dependent kinase inhibitor | |||||||||
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| Structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex.[1] | |||||||||
| Identifiers | |||||||||
| Symbol | CDI | ||||||||
| Pfam | PF02234 | ||||||||
| InterPro | IPR003175 | ||||||||
| SCOP | 1jsu | ||||||||
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A cyclin-dependent kinase inhibitor protein is a protein which inhibits cyclin-dependent kinase. Several function as tumor suppressor genes. Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (called CDIs, CKIs or CDKIs). CDIs are involved in cell cycle arrest at the G1 phase.
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